AndroVitality™
A board-certified physician's framework for understanding your male hormone panel — testosterone, free T, SHBG, LH, FSH, estradiol, prolactin, DHEA-S, cortisol, PSA, and whole-health context.
Why Men's Hormones Matter for Longevity
Testosterone and the broader hypothalamic-pituitary-gonadal (HPG) axis regulate energy, muscle mass, bone density, mood, libido, cognition, and metabolic health. Hormonal decline often begins decades before symptoms — and frequently overlaps with cardiometabolic risk.
The Testosterone Decline Curve
Total testosterone declines roughly 1–2% per year after age 30 in many men. The Endocrine Society defines biochemical hypogonadism as a consistently low morning total T (typically below ~264–300 ng/dL on two confirmed draws) accompanied by clinical symptoms.
Primary vs. Central Hypogonadism
Primary (testicular) hypogonadism shows low T with elevated LH/FSH. Central (pituitary/hypothalamic) shows low T with low or inappropriately normal LH/FSH. The distinction changes the work-up entirely — including whether pituitary imaging is warranted.
SHBG, Free T & Aromatization
Total testosterone alone can mislead. SHBG binds the majority of circulating T. Free or bioavailable T is the active fraction. Excess aromatization to estradiol — common with central adiposity and aging — can suppress the HPG axis further.
Hormones Don't Live in Isolation
Thyroid dysfunction, prolactinoma, vitamin D deficiency, insulin resistance, sleep apnea, and chronic stress all influence male hormone status. A comprehensive read evaluates the whole endocrine picture, not testosterone alone.
Don't Have Your Lab Data Yet?
You can self-order a comprehensive male hormone panel directly — no prescription or doctor visit required. Have it drawn at a national lab and use this analyzer when results return.
Order Your Men's Hormone Panel
The ULTA Men's Hormone Panel includes total & free testosterone, SHBG, LH, FSH, estradiol, prolactin, and DHEA-S — the core inputs this analyzer interprets.
* Direct lab ordering not available in NY, NJ, RI, or HI. Residents of those states should request labs through their healthcare provider. Schedule your morning draw between 7–10 a.m. for accurate testosterone values.
Enter Your Hormone & Whole-Health Values
All fields are optional — but the more biomarkers you provide, the more precise the educational interpretation. Reference ranges shown are typical adult male values; your lab's exact ranges should always be used for clinical decisions.
Analyzing Your Hormone Panel
Please wait — do not press back or refresh
- 1Classifying your HPG-axis pattern (primary vs central)…
- 2Computing free-T and SHBG-adjusted bioavailable estimates…
- 3Cross-referencing comorbidity flags (thyroid, prolactin, prostate, metabolic)…
- 4Generating personalized clinical interpretation…
This typically takes 30 to 60 seconds — we're applying validated equations and AI clinical analysis.
Accessibility
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Your Personalized Clinical Interpretation
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📄 Download PDF Report
A clean, printable report — perfect to bring to your next appointment.
📧 Email My Results
Send a copy of this analysis to your inbox for safekeeping.
Want a Board-Certified Physician to Review?
AndroVitality™ gives you a strong educational read of your hormone panel. For a physician-guided next step — review of your full results, an action plan, and personalized follow-up — Dr. Kilgore offers two options.
$225 Physician Interpretation Session
$225 · 45–60 minutes · One-on-one telemedicine
A private session with Dr. Paul Kilgore, MD, MPH, FACP, to walk through your hormone panel, address symptoms, and co-create a personalized action plan.
- Pre-session review of your AndroVitality™ results and supporting labs
- Detailed pattern interpretation (primary vs. central vs. functional)
- Discussion of evidence-based lifestyle and nutritional levers
- Guidance on appropriate next-step testing and follow-up timing
- Written summary delivered after the session
Active practice states: MI · AL · MO · WI · PA. Available to residents of any state for educational consultation.
Retest in 8–12 Weeks
From $99 · ULTA Lab Tests · No prescription needed
After lifestyle changes, treatment, or any clinical intervention, repeat testing gives you the only objective way to know whether your numbers have moved.
- Same morning draw window (7–10 a.m.) for valid comparison
- National lab network — Quest, Labcorp, or your closest location
- Results in 3–5 business days, delivered to your inbox
- Re-run AndroVitality™ on the new values to track your trajectory
* Direct lab ordering not available in NY, NJ, RI, or HI.
Evidence & Sources
AndroVitality™ is built on peer-reviewed research and major society guidelines for male hypogonadism, andrology, and integrative endocrinology. View the full bibliography on our Sources page.
📚 AndroVitality™ Sources & Citations
Endocrine Society clinical practice guideline, AUA testosterone deficiency guideline, NEJM, JCEM, and major epidemiologic studies.
Methodology — How AndroVitality™ Classifies Your Pattern
AndroVitality™ classifies your hormone panel using a deterministic clinical rule set derived from the 2018 Endocrine Society guideline on testosterone therapy in men with hypogonadism and the 2023 AUA guideline on testosterone deficiency. The AI then generates an educational interpretation grounded in your specific values and pattern.
Step 1 — Anchor Markers (Total & Free T)
- Total Testosterone: Low < 264 ng/dL · Borderline 264–399 · Normal 400–916 · High > 916
- Free Testosterone: Low < 6.4 pg/mL · Borderline 6.4–8.7 · Normal 8.7–25.1 · High > 25.1
- Both values must be interpreted in the context of morning draw timing for accuracy.
Step 2 — Gonadotropin Pattern
- Low T + elevated LH/FSH → Primary (testicular) hypogonadism
- Low T + low or normal LH/FSH → Secondary (central / pituitary-hypothalamic) hypogonadism
- Normal T + elevated LH → Compensated hypogonadism (early testicular decline)
Step 3 — Modifier Flags
- SHBG: High SHBG can produce low free T despite normal total T (common in aging, hyperthyroidism, liver disease)
- Estradiol: Elevated estradiol from aromatization can suppress HPG axis (often associated with central adiposity)
- Prolactin: Elevated prolactin can suppress GnRH and cause secondary hypogonadism (consider pituitary imaging if persistently >20 ng/mL)
- DHEA-S: Low values may indicate adrenal androgen decline; high values may indicate adrenal pathology
- Cortisol AM: Markers of HPA dysregulation that often coexist with HPG suppression
- PSA: Critical baseline safety marker; elevation requires urology referral before any androgen-modifying therapy
Step 4 — Whole-Health Context
- TSH: Thyroid dysfunction can mimic or worsen hypogonadism symptoms and alter SHBG
- Vitamin D < 30 ng/mL: Associated with lower testosterone in observational cohorts
- HbA1c ≥ 5.7%: Insulin resistance suppresses both total and free T
- ApoB / LDL-C: Cardiometabolic risk markers that frequently track with low T
Important Limits
AndroVitality™ is educational and does not diagnose. Reference ranges vary by laboratory; the ranges shown reflect typical Quest/Labcorp adult male assays. Any biochemical hypogonadism must be confirmed on two morning draws with concurrent clinical symptoms before any therapy is considered. Testosterone replacement is a controlled-substance therapy in the United States and requires in-person clinical evaluation.
Important Notices
AndroVitality™ is provided by Quantitative Health LLC for educational and informational purposes only. It does not provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
The personalized interpretation in this tool is generated with the assistance of Anthropic's Claude language model, operating under a physician-authored clinical framework with regulatory guardrails. AI-generated content is reviewed against a deterministic clinical rule set but may contain errors or omissions. Full details: drpaulkilgore.com/ai-disclosure.
Your hormone values and any other inputs are processed privately to generate this report. No information is permanently stored on our servers; values are not linked to advertising, marketing profiles, or third-party data brokers. If you choose to email yourself a copy, only your name, email address, and report content are transmitted to our email delivery service (Resend) for that single delivery.
AndroVitality™ analyzes the values you provide against typical adult-male reference ranges. It cannot detect lab error, account for medications affecting hormone assays, recognize secondary causes beyond the input panel (e.g., pituitary adenomas without imaging), or substitute for a clinical examination. Reference ranges shown are general — your laboratory's ranges should always be used for clinical decisions.
Testosterone and related androgens are Schedule III controlled substances in the United States. AndroVitality™ does not prescribe, recommend specific doses, or facilitate the procurement of testosterone or any other hormone therapy. Decisions about testosterone replacement therapy must be made with a licensed physician after appropriate in-person clinical evaluation, confirmed biochemical hypogonadism, and a discussion of risks, benefits, and alternatives.
This tool is designed to meet WCAG 2.2 Level AA accessibility standards. A floating accessibility menu (bottom-right of the page) provides options for text resizing and high-contrast mode. If you encounter any accessibility barrier, please contact us at [email protected].
If you are experiencing a medical emergency — chest pain, severe symptoms, suicidal thoughts, or acute distress — do not use this tool. Call 911 (or your local emergency number) or go to your nearest emergency department immediately. For mental-health crisis support in the U.S., call or text 988 (Suicide & Crisis Lifeline).
